Anti-A2M Polyclonal Antibody-抗体-抗体-生物在线
Anti-A2M Polyclonal Antibody

Anti-A2M Polyclonal Antibody

商家询价

产品名称: Anti-A2M Polyclonal Antibody

英文名称: A2MD;CPAMD5;FWP007;S863-7

产品编号: K002843P

产品价格: null

产品产地: 北京

品牌商标: Solarbio

更新时间: null

使用范围: WB IF

北京索莱宝科技有限公司--实验室产品
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  • 邮箱 : 2748554845@qq.com

The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified.